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The mission of the Viral Vector Core is to pave the way for gene delivery in neuroscience research. The Viral Vector Core is focused on high-titer, high-throughput production of Lentiviral vectors to deliver and express interested genes in either dividing or non-dividing mammalian cells, primary culture and in vivo in animal models. These vector systems are also being modified according to the different research requirements. Because of its packaging size and relative ease of production, Lentiviral vectors are the chosen vector as a useful tool in the discoveries of the molecular basis of neurological disease and in gene therapy.

Researchers must provide lentiviral plasmid DNA to the core for production.  The common lentiviral vector plasmids are available from the core, and researchers can discuss cloning strategies with the core director.  However, the vector core is not staffed to do the cloning of new vectors for individual researchers.

A fee for service is charged per vector production. The Viral Vector Core is partially subsidized by the NINDS and CND, and this subsidy will apply to those who are a part of these organizations. Investigators interested in getting more information on the Viral Vector Core including the fee schedule should contact Nancy Ciliax at 404/727-4927 or .