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Daniel Huddleston, MD

Assistant Professor
Department of Neurology

Phone: 404-778-3444


Daniel Huddleston, MD, is a movement disorders neurologist and MRI researcher at Emory University. He is board certified in adult neurology, and his clinical interests include Parkinson’s disease and related conditions. These include dementia with Lewy bodies, Parkinson’s disease dementia, progressive supranuclear palsy and multiple system atrophy. Dr. Huddleston also specializes in the diagnosis and treatment of various types of tremor. He performs Botox injections to treat conditions including cervical dystonia (torticollis), blepharospasm, hemifacial spasm, limb spasticity related to stroke and cerebral palsy, and sialorrhea (drooling). He graduated from Dartmouth College, and then completed his medical school training at the Columbia University College of Physicians and Surgeons in New York City. He carried out neurology residency at Columbia University Medical Center, and then came to Emory for a 2-year fellowship in movement disorders. He joined the Emory Faculty in 2016.

Dr. Huddleston’s MRI neuroscience laboratory focuses on the development of MRI and multimodality biomarkers for Parkinson’s disease and related disorders. An overarching goal of this work is to develop MRI tools that can assist the differential diagnosis of these conditions, and to make clinical trials for parkinsonian disorders more successful. Potential applications of these biomarkers include early detection, subject selection for trials, outcome measurement, therapeutic target identification and companion diagnostic use. This translational niche allows Dr. Huddleston to pursue neuroscience research with a commitment to improve patients’ lives.

As Principal Investigator of the Emory Lewy Body Dementia Association Research Center of Excellence, Dr. Huddleston is a leader in the effort to improve clinical care and research for dementia with Lewy bodies and Parkinson’s disease dementia. He is also the Emory Site Principal Investigator for the North American Prodromal Synucleinopathy (NAPS) Consortium, which is a multi-center group devoted to identifying Parkinson’s disease and related conditions prior to the onset of symptoms. In addition, he is Co-Principal Investigator of a longitudinal MRI study of Parkinson’s disease funded by the Michael J. Fox Foundation, as well as Principal Investigator of a Georgia Research Alliance Phase I Award to develop MRI technology to assist accurate diagnosis of Parkinson’s disease.

Dr. Huddleston grew up in Knoxville, TN. Outside of medicine and science, Dr. Huddleston’s favorite activities are spending time with his wife and two children, playing tennis, biking on the Silver Comet Trail, and rooting for the Braves.