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Rangaraju Laboratory

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We study immune responses in the brain, focusing on microglia and brain-resident macrophages in states of health and neurological diseases. Our research methods include rodent models of neurodegeneration and acute neuroinflammation and we employ flow cytometric, transcriptomic and proteomic profiling methods to study microglia and CNS macrophages in addition to performing in-vitro assays of microglial and macrophage effector functions. We are developing novel therapeutics that can selectively inhibit pro-inflammatory immune responses in neurodegenerative diseases while sparing and augmenting protective and phagocytic microglial responses. We are located in the Whitehead Research Building at Emory University and our lab in embedded within the Emory Center for Neurodegenerative Diseases.